Dopamine Injection 200Mg/5Ml

Name: Dopamine Injection 200Mg/5Ml
Brand: LAHORE CHEMICAL
Price: 171

Brand : lahore chemical

Rs. 171.00

Rs. 180.00

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Dopamine Injection Specification

Requires Prescription (YES/NO)

Yes

Generics

Dopamine

Used For

Heart Failure

How it works

Dopamine hydrochloride can stimulate alpha, beta and dopamine receptors. At infusion rates of 0.5 to 2 micrograms/kg/min, dopamine receptors are selectively activated and blood pressure either does not change or decreases slightly. The most important effects are renal and mesenteric vasodilatation. Renal plasma flow, glomerular filtration rate and sodium excretion usually increase. At infusion rates of 2 to 10 micrograms/kg/min, beta1-receptors are activated and cardiac output and systolic blood pressure increase. The total peripheral resistance is relatively unchanged because of peripheral vasoconstriction (alpha effect) and muscle vasodilatation (beta effect). At infusion rates above 10 micrograms/kg/min, alpha-receptors are activated, causing vasoconstriction, and both systolic and diastolic pressures increase. Dopamine does not cross the blood-brain barrier and so does not activate dopamine receptors in the brain.

Dopamine Injection Usage And Safety

Dosage

Dopamine

Side Effects

Nausea and vomiting , peripheral vasoconstriction , hypotension , hypertension , tachycardia .

Drug Interactions

MAO inhibitors , alpha-and beta-adrenergic blockers , cocaine , generate anaesthesia , methyldopa , phenytoin , reserpine , TCAs , guanethidine .

Indication

It is used to treat cardiogenic shock in infarction or cardiac surgery .

When not to Use

Administration of dopamine is contraindicated in the following cases : Pheochromocytoma: dopamine may release catecholamines into the circulation, producingan additive effect to an already abnormally high catecholamine level, and causing acute hypertension. Atrial or ventricular tachyarrhythmias or ventricular fibrillation . Concurrent use with cyclopropane and halogenated hydrocarbon anesthetics .

Dopamine Injection Precautions

Precaution

Patients who are taking Monoamine oxidase (MAO) inhibitors or who have taken them within the last two to three weeks require a substantially reduced starting dose, i.e. about 1/10th the usual dose .

Dopamine Injection Warnings

Warning 1

Excessive dosage may be indicated by a disproportionate rise in diastolic pressure (ie. a marked decrease in pulse pressure). The infusion rate should be decreased or ceased and the patients observed carefully for further evidence of predominant vasoconstriction activity, unless such an effect is desired.

Warning 2

Acidosis, hypercapnia or hypoxia may reduce the effectiveness and/or increase the incidence of adverse effects of dopamine. These conditions should be corrected prior to or concurrently with administration of dopamine .

Warning 3

Hypotension may occur when attempting to wean patients from dopamine and it may be necessary to substitute dopamine with another pressor agent or to expand blood volume whilst gradually reducing the infusion rate.