Pirfenox Tablets 200Mg (1 Box = 5 Strips) (1 Strip = 10 Tablets)
Brand : highnoon laboratories ltd.
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Pirfenox Tablets Specification
Requires Prescription (YES/NO)
Yes
Generics
Pirfenidone
Used For
Lung Disorder
How it works
Pirfenidone is a medicine that aims to slow down the development of scar tissue in the lungs. We do not know how this process works. It does not cure or reverse the scarring but, by slowing down how quickly the scarring occurs, pirfenidone may slow down the progression of idiopathic pulmonary fibrosis (IPF).
Pirfenox Tablets Usage And Safety
Dosage
Pirfenidone
Side Effects
? Infections of the throat or the airways going into the lungs and/or sinusitus ? Feeling sick (nausea) ? Stomach problems such as acid reflux, vomiting and feeling constipated ? Diarrhoea ? Indigestion or stomach upset ? Weight loss ? Decreased appetite ? Difficulty sleeping ? Tiredness ? Dizziness ? Headache ? Shortness of breath ? Cough ? Aching joints/joint pains ? Bladder infections ? Feeling sleepy ? Changes in taste ? Hot flushes ? Stomach problems such as feeling bloated, abdominal pain and discomfort, heart burn, and passing wind ? Blood tests may show increased levels of liver enzymes .
Drug Interactions
? Enoxacin ? Ciprofloxacin ? Amiodarone ? Propafenone ? Fluvoxamine ? Omeprazole ? Rifampicin .
Indication
It is indicated for the treatment of Idiopathic Pulmonary fibrosis (IPF).
When not to Use
Do not take ? If you are allergic to pirfenidone or any of the other ingredients of this medicine ? If you have previously experienced angioedema with pirfenidone, including symptoms such as swelling of the face, lips and/or tongue which may be associated with difficulty breathing or wheezing ? If you are taking a medicine called fluvoxamine (used to treat depression and obsessive compulsive disorder [OCD]) ? If you have severe or end stage liver disease ? If you have severe or end stage kidney disease requiring dialysis.
Pirfenox Tablets Precautions
Precaution
If a patient exhibits an aminotransferase elevation to >3 to =5 x ULN after starting pirfenidone therapy, confounding medicinal products should be discontinued, other causes excluded, and the patient monitored closely. If clinically appropriate the dose of pirfenidone should be reduced or interrupted. Once liver function tests are within normal limits pirfenidone may be re-escalated to the recommended daily dose if tolerated.
Pirfenox Tablets Warnings
Warning 1
Exposure to direct sunlight (including sunlamps) should be avoided or minimised during treatment with pirfenidone. Patients should be instructed to use a sunblock daily, to wear clothing that protects against sun exposure, and to avoid other medicinal products known to cause photosensitivity. Patients should be instructed to report symptoms of photosensitivity reaction or rash to their physician. Severe photosensitivity reactions are uncommon. Dose adjustments or temporary treatment discontinuation may be necessary in mild to severe cases of photosensitivity reaction or rash .
Warning 2
Reports of angioedema (some serious) such as swelling of the face, lips and/or tongue which may be associated with difficulty breathing or wheezing have been received in association with use of pirfenidone in the post-marketing setting. Therefore, patients who develop signs or symptoms of angioedema following administration of pirfenidone should immediately discontinue treatment. Patients with angioedema should be managed according to standard of care. Pirfenidone should not be used in patients with a history of angioedema due to pirfenidone .
Warning 3
Dizziness has been reported in patients taking pirfenidone. Therefore, patients should know how they react to this medicinal product before they engage in activities requiring mental alertness or coordination . In clinical studies, most patients who experienced dizziness had a single event, and most events resolved, with a median duration of 22 days. If dizziness does not improve or if it worsens in severity, dose adjustment or even discontinuation of pirfenidone may be warranted .
Pirfenox Tablets Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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