Clopixol-Acuphase Injection 100Mg/2Ml

Brand : lundbeck pakistan (pvt) ltd

Rs. 659.30

Rs. 694.00

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Clopixol-Acuphase Injection Specification

Requires Prescription (YES/NO)

Yes

Generics

Zuclopenthixol Acetate

Used For

Schizophrenia

How it works

It contains the active substance zuclopenthixol. It belongs to a group of medicines known as antipsychotics (also called neuroleptics). These medicines act on nerve pathways in specific areas of the brain and help to correct certain chemical imbalances in the brain that are causing the symptoms of your illness.

Clopixol-Acuphase Injection Usage And Safety

Dosage

Zuclopenthixol Acetate

Side Effects

• Reduction in blood platelets (which increases the risk of bleeding or bruising) and other blood cell changes. • Drowsiness • Loss of co-ordination or altered muscle movements (including unusual movements of the mouth, tongue and eyeballs) • Tremor • Stiff or floppy muscles (including stiff jaw and neck muscles) • Dizziness or vertigo • Headache or migraine • Numbness or tingling in the arms and legs • Poor concentration, loss of memory or confusion • A changed walking pattern • Abnormal reflexes • Rigidity of the whole body • Fainting • Speech problems • Fits • Enlarged pupils or blurred, abnormal vision • Sensitive hearing or ringing in the ears (tinnitus) • Stuffy nose • Shortness of breath • Dry mouth or increase in saliva • Feeling sick or vomiting • Indigestion or stomach pain.

Drug Interactions

• Tricyclic antidepressants • Barbiturates • Anticoagulant drugs (e.g. warfarin) • Anticholinergic drugs (contained in some cold, allergy or travel sickness remedies as well• Metoclopramide (used to treat nausea and other stomach conditions) • Piperazine (used to treat worm infections) • Levodopa or other medicines used to treat Parkinson’s disease • Sibutramine (used to reduce appetite) • Digoxin (to control heart rhythm) • Corticosteroids (e.g. prednisolone) • Medicines used to lower the blood pressure such as hydralazine, alpha blockers (e.g. doxazosin) beta-blockers, methyldopa, clonidine or guanethidine .

Indication

It is used for the treatment of schizophrenia and other psychosis.

When not to Use

It is not given if you are allergic (hypersensitive) to zuclopenthixol, other thioxanthene drugs or antipsychotic drugs or any of the other ingredients of this medicine . Tell your doctor If you are feeling less alert than usual, or are drowsy or sleepy or have serious problems with your blood circulation .

Clopixol-Acuphase Injection Precautions

Precaution

Zuclopenthixol should be used with caution in patients with Parkinsonism, as it is known that dopamine antagonists such as zuclopenthixol, can cause a deterioration of the disease.

Clopixol-Acuphase Injection Warnings

Warning 1

As with other drugs belonging to the therapeutic class of antipsychotics, zuclopenthixol may cause QT prolongation. Persistenly prolonged QT intervals may increase the risk of malignant arrhythmias. Therefore, zuclopenthixol should be used with caution in susceptible individuals (with hypokalemia, hypomagnesia or genetic predisposition) and in patients with a history of cardiovascular disorders.

Warning 2

Cases of venous thromboembolism (VTE) have been reported with antipsychotic drugs. All possible risk factors for VTE should be identified before and during treatment with zuclopenthixol and preventive measures undertaken.

Warning 3

Zuclopenthixol should be used with caution in patients with a history of convulsive disorders, as drugs of this class are known to lower seizure threshold .