Combihale Nebulization Specification
Requires Prescription (YES/NO)
Yes
Generics
Ipratropium Bromide , Salbutamol Sulphate
Used For
Chronic Obstructive Pulmonary Disease
How it works
The active ingredients are ipratropium bromide and salbutamol sulfate. Ipratropium bromide and salbutamol both belong to a group of medicines called bronchodilators, which help to improve your breathing by opening up your airways. This is achieved by preventing the contraction of the smooth muscles surrounding the airways, therefore allowing the airways to remain open. Ipratropium bromide acts by blocking the nerve signals that go to the muscles surrounding the airways, and salbutamol acts by stimulating specific receptors in the muscles.
Combihale Nebulization Usage And Safety
Dosage
Ipratropium Bromide , Salbutamol Sulphate
Side Effects
Upper respiratory tract infection ; Nasopharyngitis ; Cough ; Bronchitis ; Headache ; Dyspnea .
Drug Interactions
Beta-Agonists , xanthine derivatives and corticosteroids , MAOIs or TCAs , Inhalation of halogenated hydrocarbon anaesthetics such as halothane , trichloroethylene and enflurane .
Indication
For the treatment of bronchospasm associated with Chronic Obstructive Pulmonary Disease (COPD) and asthma.
When not to Use
Contraindicated in patients with hypertrophic obstructive cardiomyopathy, tachyarrhythmia or a history of hypersensitivity to salbutamol or Ipratropium Bromide.
Combihale Nebulization Precautions
Precaution
Discontinue immediately if paradoxical bronchospasm, hypersensitivity or visual disturbances occur. Use with caution in patients with cardiovascular system disorders and narrow angle glaucoma.
Combihale Nebulization Warnings
Warning 1
Patients with underlying severe heart disease ( e.g . ischaemic heart disease , arrthymia or severe heart failure ) who are receiving Salbutamol for respiratory disease , should be warned to seek medical advice if they experience chest pain or symptoms of worsening heart disease . Attention should be paid to assessment of symptoms such as dyspnoea and chest pain , as they may be of either respiratory or cardiac origin.
Warning 2
Patients with cystic fibrosis may be more prone to gastro-intestinal motility disturbances .
Warning 3
Inhaled medicines, including tiotropium, may cause paradoxical bronchospasm. If this occurs, it should be treated immediately with an inhaled short acting beta2-agonist such as salbutamol. Treatment with tiotropium should be stopped and other treatments considered.
Combihale Nebulization Additional Information
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
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