Depo-Medrol Injection 80Mg/2Ml

Brand : pfizer laboratories

Rs. 328.70

Rs. 346.00

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Depo-Medrol Injection Specification

Requires Prescription (YES/NO)

Yes

Generics

Methylprednisolone Acetate

Used For

Allergy

How it works

It is a sterile aqueous suspension of the synthetic glucocorticoid methylprednisolone acetate. It has a strong and prolonged anti-inflammatory, immunosuppressive and anti-allergic activity. It can be administered I.M. for a prolonged systemic activity as well as In Situ for a local treatment. The prolonged activity of this medicine is explained by the slow release of the active substance .

Depo-Medrol Injection Usage And Safety

Dosage

Methylprednisolone Acetate

Side Effects

Allergic reactions: Angioedema. Blood and lymphatic system disorders: Leukocytosis Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, cardiac failure congestive (in susceptible patients), fat embolism, hypertension, hypotension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction, pulmonary oedema, syncope, tachycardia, thromboembolism, thrombophlebitis, thrombosis, vasculitis. Dermatologic: Acne, allergic dermatitis, dry scaly skin, ecchymoses and petechiae, oedema peripheral, erythema, skin hyperpigmentation, skin hypopigmentation, impaired healing, rash, abscess sterile, skin striae, suppressed reactions to skin tests, skin atrophy, thinning scalp hair, urticaria, angioedema, pruritus, hyperhidrosis, injection site reaction and injection site infection. Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy .

Drug Interactions

Live vaccines or other vaccines , anticoagulants , hypoglycaemic agents , antihypertensives , diuretics , erythromycin , rifamycin , amphotericin , azole antifungals , ritonavir , cyclosporin , cardiac glycosides . Oestrogens including oral contraceptives , somatropin. Carbamazepine , phenytoin , primidone , barbitturates . Muscle relaxants , NSAIDs , salicylates , sympathomimetics , mifepristone , methotrexate , theophylline , asprepitant .

Indication

Corticosteroid responsive conditions such as hay fever , asthma , rheumatoid arthritis , osteoarthritis , collagen disease , dermatoses.

When not to Use

It is contraindicated: In patients with known hypersensitivity to any components of the product , In patients with systemic fungal infections , In idiopathic thrombocytopenic purpura when administered intramuscularly .

Depo-Medrol Injection Precautions

Precaution

It should not be administered by any route other than those listed. It is critical that, during administration of this medicine , appropriate technique be used and care taken to assure proper route of administration.

Depo-Medrol Injection Warnings

Warning 1

Kaposi’s sarcoma has been reported to occur in patients receiving corticosteroid therapy. Discontinuation of corticosteroids may result in clinical remission.

Warning 2

Appropriate examination of any joint fluid present is necessary to exclude a septic process. A marked increase in pain accompanied by local swelling, further restriction of joint motion, fever and malaise are suggestive of septic arthritis. If this complication occurs and the diagnosis of sepsis is confirmed, appropriate antimicrobial therapy should be instituted.

Warning 3

Thrombosis including venous thromboembolism has been reported to occur with corticosteroids. As a result corticosteroids should be used with caution in patients who have or may be predisposed to thromboembolic disorders.