Dvago Logo
    location icon

    rightArrow
    Dvago Logo

    Delivers in

      location icon

      rightArrow
      Dvago

      Domel Tablets 10 Mg

      Rs. 428.50

      Rs. 451.00

      |

      QUICK DELIVERY

      Domel Tablets Specification

      Requires Prescription (YES/NO)

      Yes

      Generics

      Domeperidone Maleate

      Used For

      Nausea & Vomiting

      How it works

      Its anti emetic effect may be due to a combination of peripheral (gastrokinetic) effects and antagonism of dopamine receptors in the chemoreceptor trigger zone, which lies outside the blood brain barrier in the area postrema.

      Domel Tablets Usage And Safety

      Dosage

      Domeperidone Maleate

      Side Effects

      Depression (2.5%) Anxiety (1.6%) Libido Decreased/Loss of Libido , Headache (5.6%) , Somnolence (2.5%) , Akathisia (1%) , Diarrhea (5.2%) , Rash (2.8%), Pruritus (1.7%) , Breast Enlargement / Gynaecomastia (5.3%) Breast Tenderness (4.4%), Galactorrhoea (3.3%) , Amenorrhea (2.9%) , Breast Pain (2.3%), , Menstruation Irregular (2.0%) , Lactation Disorder (1.6%).

      Drug Interactions

      CYP3A4 inhibitors such as indinavir , Anti arrhythmics class IA (e.g., disopyramide, quinidine), anti arrhythmics class III (e.g., amiodarone, dofetilide, dronedarone, ibutilide, sotalol), certain antipsychotics (e.g., haloperidol, pimozide, sertindole), certain antidepressants (e.g., citalopram, escitalopram), certain antibiotics (e.g., levofloxacin, moxifloxacin), certain antifungal agents (e.g., pentamidine), certain antimalarial agents (e.g., halofantrine), certain gastro intestinal drugs (e.g., dolasetron), certain drugs used in cancer (e.g., toremifene, vandetanib), certain other drugs (e.g., bepridil, methadone).

      Indication

      It is used in the treatment of nausea and vomiting.

      When not to Use

      Domeperidone is contraindicated in the following situations: • In patients with moderate to severe hepatic impairment • In patients who have known existing prolongation of cardiac conduction intervals (particularly QTc) and in patients with significant electrolyte disturbances or underlying cardiac diseases such as congestive heart failure.

      Domel Tablets Precautions

      Precaution

      Epidemiological studies have shown domperidone may be associated with an increased risk of serious ventricular arrhythmias or sudden cardiac death.

      Domel Tablets Warnings

      Warning 1

      Patients older than 60 years of age should consult their physician before taking domeperidone maleate.

      Warning 2

      Due to increased risk of ventricular arrhythmia, domeperidone maleate is not recommended in patients with known existing prolongation of cardiac conduction intervals, particularly QTc, in patients with significant electrolyte disturbances.

      Warning 3

      Treatment with domeperidone maleate should be stopped if signs or symptoms occur that may be associated with cardiac arrhythmia, and the patient should promptly consult their physician.

      Domel Tablets Additional Information

      Pregnancy category

      Always consult your physician before using any medicine.

      Storage (YES/NO)

      Store this medicine at room temperature, away from direct light and heat.

      Related Products