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enoxabid tablets 400mg (1 strip = 10 tablets) Product Image

Enoxabid Tablets 400Mg (1 Strip = 10 Tablets)

Brand : abbot laboratories (pak) ltd

Rs. 0.00

Rs. 0.00

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Enoxabid Tablets Specification

Requires Prescription (YES/NO)

Yes

Generics

Enoxacin Sesquihydrate

Used For

Bacterial Infection

How it works

Enoxacin blocks DNA synthesis during bacterial replication by inhibiting the bacterial enzyme DNA gyrase. It has a broad antibacterial spectrum against Gram-positive and Gram-negative bacteria at bioavailable concentrations achievable in body tissues and fluids.

Enoxabid Tablets Usage And Safety

Dosage

Enoxacin Sesquihydrate

Side Effects

Renal: Acute renal failure may rarely occur and transient elevation in BUN and serum creatinine levels have been occasionally observed. Hematologic: Transient increases in eosinophil counts and decreases in leucocyte counts, thrombocyte counts and hemoglobin levels may infrequently occur. If any such abnormalities are observed, adminstration should be discontinued. Gastrointestinal: Nausea, vomiting, anorexia, abdominal pain, discomfort, diarrhoea, constipation may infrequently occur and stomatitis may rarely occur. Severe colitis associated with bloody stool, such as pseudomembranous colitis, has also been reported with the use of other new quinolones, If abdominal pain or frequent diarrhoea develops the drug must be discontinued and appropriate measures taken. Elevation of SGOT, SGPT, and ALP, may infrequently occur and increase of bilirubin may rarely occur. Central Nervous System: Dizziness, headache and insomnia may infrequently occur and convulsions, drowsiness, feeling of numbness, tinnitus, light headache feeling, tremor or dull headache may rarely occur. Peripheral neuropathy that may be irreversible Muscular: Rhabdomyolysis occurring with acute renal function disorder, characterized by myalgias, weakness, elevation of CPK, and elevation of plasma/urine myoglobin level, may occur. Therefore, appropriate precautions should be taken. Skin: Since Lyell syndrome and Stevens Johnson syndrome may occur rarely, the patient must be monitored carefully. Administration of Enoxacin must be discontinued when any abnormality is observed and the patient should be treated appropriately. Others: Palpitation, precordial discomfort, malaise, hypoglycemic symptoms, diminished taste or backache may rarely occur.

Drug Interactions

Concurrent use of Enoxacin with theophylline has been reported to enhance the effects of theophylline by elevating its serum level. Therefore, the dosage of theophylline should be reduced during concurrent therapy. There is a possibility of convulsive episodes caused by the concomitant use of Enoxacin with non-steroidal anti-inflammatory analgesics of the phenylacetic acid or propionic acid group (e.g. fenbufen and, therefore, co-administration should be done carefully. Concurrent administration of antacids containing magnesium hydoroxide or aluminum hydroxide may interfere with the absorption of Enoxacin resulting in serum levels lower than desired for therapy against some organisms.

Indication

It is indicated in the following infections caused by susceptible organisms:Upper Respiratory Tract / ENT: Pharyngitis, peritonsillar abscess, otitis media, sinusitis.Lower Respiratory Tract: Acute bronchitis, acute exacerbations of chronic bronchitis, bronchiectasis with infection, pneumonia and lung abscess.Skin/Skin Structures: Folliculitis, furunculosis, carbuncles, impetigo, cellulitis, secondary infections of wounds, burns and surgical incisions.Urinary Tract: Acute/simple and chronic/complicated urinary tract infections, including cystitis, pyelonephritis and prostatitis.Sexually Transmitted Diseases: Gonococcal urethritis. GI Tract: Bacillary dysentery and enteritis, Typhoid (enteric fever)

When not to Use

It is contraindicated in patients who have known hypersensitivity to this antimicrobial agent or other quinolones

Enoxabid Tablets Precautions

Precaution

It should be carefully administered to patients with: - Severe renal dysfunction or undergoing hemodialysis. This drug is only removed slightly by hemodialysis.

Enoxabid Tablets Warnings

Warning 1

Peripheral Neuropathy: Cases of sensory or sensorimotor axonal polyneuropathy aecting small and / or large axons resulting in paresthesias, hypoesthesias, dysesthesias and weakness have been reported in patients receiving fluoroquiolones.

Warning 2

Vision disorders:The association between fluoroquinolone intake and occurrence of retinal detachment has been investigated in several epidemiological studies using various designs and data sources. Studies have found a statistically significant increased risk. Therefore, small increase in risk cannot be excluded, especially in patients with risk factors.

Warning 3

Always consult your physician before using any medicine.

Enoxabid Tablets Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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