Fluanxol Depot Injection 40Mg/2Ml

Brand : lundbeck pakistan (pvt) ltd

Rs. 809.14

Rs. 851.73

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Fluanxol Depot Specification

Requires Prescription (YES/NO)

Yes

Generics

Flupentixol Decanoate

Used For

Schizophrenia

How it works

Flupentixol is a thioxanthene derivative with antipsychotic properties. The exact mechanism of action of flupentixol has not been established. Its effects resemble those of the phenothiazine, fluphenazine, in that it belongs among the antipsychotic drugs which are less likely to cause sedation and hypotension, but have greater propensity for producing extrapyramidal reactions.

Fluanxol Depot Usage And Safety

Dosage

Flupentixol Decanoate

Side Effects

Neurological: Extrapyramidal symptoms may occur, especially during the early phase of treatment. In most cases these side effects can be satisfactorily controlled by reduction of dosage and/or antiparkinsonian drugs. The routine prophylactic use of antiparkinsonian medication is not recommended. Tardive dyskinesias may occur very occasionally in patients on long-term therapy. Antiparkinsonian drugs do not alleviate these symptoms. Reduction in dosage or, if possible, discontinuation of therapy is recommended. Psychic: Transient insomnia, especially when the patient is switched over from sedative neuroleptics. At high dosage a sedative effect may occur in the occasional patient. Autonomic and cardiovascular: Very rare in the therapeutic dosage range. Liver: Transient slight alterations in liver function tests may occur. Fluanxol, even in low doses, in susceptible (especially non-psychotic) individuals may unusually cause nausea, dizziness or headache, excitement, agitation, insomnia, or unpleasent subjective feelings of being mentally dulled or slowed down. Epileptic fits have occasionally been reported. Confusional states can occur.

Drug Interactions

Barbiturates and other CNS depressants , guanethidine or similar acting compounds, levodopa , metoclopramide and piperazine , adrenaline and other sympathomimetic agents , guanethidine, quinidine , corticosteroids and digoxin, diazoxide and neuromuscular blocking agents , erythromycin , moxifloxacin .

Indication

It is used for the long-term treatment of schizophrenia, a mental illness with disturbances in thinking, emotional reactions and behaviour, and other chronic mental conditions .

When not to Use

* Patients with known hypersensitivity to thioxanthenes, flupentixol or to any ingredient in the formulation or component of the container. * The possibility of crosssensitivity between the thioxanthenes and phenothiazine derivatives should be considered. ? Alcohol, barbiturate or opiate intoxication. * Patients with CNS depression due to any cause, comatose states, suspected or established subcortical brain damage or circulatory collapse .

Fluanxol Depot Precautions

Precaution

Caution should be used when using flupentixol in patients with severe arteriosclerosis or in those who may have a propensity for development of defects in cardiac conduction.

Fluanxol Depot Warnings

Warning 1

Although its anticholinergic properties are relatively weak, flupentixol should be used with caution in patients who are known or are suspected to have glaucoma.

Warning 2

Caution should also be taken in patients who might be exposed to extreme heat, or organophosphorus insecticides or who are receiving atropine or related drugs. Paralytic ileus has occasionally been reported, particularly in the elderly, when several drugs with anticholinergic effects have been used simultaneously.

Warning 3

The antiemetic effect observed with flupentixol in animal studies may also occur in man; therefore, the drug may mask signs of toxicity due to overdosage of other drugs, or it may mask the symptoms of disease, such as brain tumour or intestinal obstruction.