This medicine is use or the relief of pain associated with peptic ulcer disease or esophagitis. It is also used topically in the management of hemorrhoid pain.

Constipation, headache, nausea and loss of appetite,drowsiness.these side effects are associated with oral use only.

Hypersensitivity to the active ingredients.

Before using it, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.).

Do not use it for more than 2 weeks unless instructed by your doctor

Report immediately to doctor if experiencing confusion, unusual tiredness, muscle weakness

Take your other medications 1 hour before or 2 hours after this medication

There appears to be no risk when taking this drug during pregnancy.

This product may react with other medications (including digoxin, iron, pazopanib, tetracycline antibiotics, quinolone antibiotics such as ciprofloxacin), preventing them from being fully absorbed by your body. Talk with your doctor or pharmacist about how to schedule your medications to prevent this problem