Nerisone 0.30% Forte Fatty Ointment 10Gm

Brand : bayer pharma (pvt) ltd.

Rs. 273.51

Rs. 287.90

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Nerisone 0.30% Specification

Requires Prescription (YES/NO)

Yes

Generics

Diflucortolone Valerate

Used For

Eczema

How it works

The mechanism of anti-inflammatory activity of topical corticosteroids is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostagladins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.

Nerisone 0.30% Usage And Safety

Dosage

Diflucortolone Valerate

Side Effects

Pruritus, local skin burning /skin pain, allergic contact dermatitis/dermatitis, dryness folliculitis, acneiform eruptions, perioral dermatitis, erythema, rash, urticaria, pustular psoriasis, skin thinning /skin atrophy , skin wrinkling , skin dryness , striae , telangiectasias , pigmentation changes , hypertrichosis, exacerbation of underlying symptoms, alopecia, trichorrhexis, and miliaria.

Drug Interactions

Co-administered drugs that can inhibit CYP3A4 (e.g., ritonavir, itraconazole) have been shown to inhibit the metabolism of corticosteroids leading to increased systemic exposure. The extent to which this interaction is clinically relevant depends on the dose and route of administration of the corticosteroids and the potency of the CYP3A4 inhibitor.

Indication

All dermatoses which respond to topical corticosteroid therapy . Not suitable for peri-oral dermatitis and rosacea.

When not to Use

Patients who are hypersensitive to this drug or to any ingredient in the formulation or component of the container, Patients who are hypersensitive to other corticosteroids , Skin diseases in infants under one year of age.

Nerisone 0.30% Precautions

Precaution

Patients should be advised to inform subsequent physicians of the prior use of corticosteroids.

Nerisone 0.30% Warnings

Warning 1

Suitable precautions should be taken when using topical corticosteroids in patients with stasis dermatitis and other skin diseases associated with impaired circulation.

Warning 2

Use of corticosteroids around chronic leg ulcers may be associated with a higher occurrence of local hypersensitivity reactions and an increased risk of local infection.

Warning 3

Pediatric patients may absorb larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity from equivalent doses because of their larger skin surface to body mass ratios as compared with adult patients .