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      Dvago

      Seroft Tablets 50 Mg

      Rs. 396.80

      Rs. 417.64

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      Seroft Tablets Specification

      Requires Prescription (YES/NO)

      Yes

      Generics

      Sertraline HCl

      Used For

      Depression

      How it works

      Sertraline potentiates serotonergic activity in the central nervous system through inhibition of neuronal reuptake of serotonin (5-HT).

      Seroft Tablets Usage And Safety

      Dosage

      Sertraline HCl

      Side Effects

      Hypersensitivity reactions to sertraline , Disulfiram-alcohol reaction when ZOLOFT oral solution is taken with disulfiram , QT prolongation and ventricular arrhythmias when taken with pimozide , Suicidal thoughts and behaviors , Serotonin syndrome , Increased risk of bleeding , Activation of mania/hypomania , Discontinuation syndrome , Seizures , Angle-closure glaucoma , Hyponatremia.

      Drug Interactions

      Selegiline, tranylcypromine, isocarboxazid, phenelzine, linezolid, methylene blue , other SSRIs, SNRIs, triptans, tricyclic antidepressants, fentanyl, lithium, tramadol, tryptophan, buspirone, St. John’s Wort, aspirin, clopidogrel, heparin, warfarin , propafenone, flecainide, atomoxetine, desipramine, dextromethorphan, metoprolol, nebivolol, perphenazine, thoridazine, tolterodine, venlafaxine , fosphenytoin .

      Indication

      Sertraline HCl is indicated for the treatment of the following *Major depressive disorder (MDD) * Obsessive-compulsive disorder (OCD) * Panic disorder (PD)

      When not to Use

      It is contraindicated in patients:-Taking, or within 14 days of stopping, MAOIs, (including the MAOIs linezolid and intravenous methylene blue) because of an increased risk of serotonin syndrome.- Taking pimozide- With known hypersensitivity to sertraline (e.g., anaphylaxis, angioedema).

      Seroft Tablets Precautions

      Precaution

      Exposure to SSRIs and SNRIs, including sertraline HCl in late pregnancy may lead to an increased risk for neonatal complications requiring prolonged hospitalization, respiratory support, and tube feeding, and/or persistent pulmonary hypertension of the newborn (PPHN).

      Seroft Tablets Warnings

      Warning 1

      Serotonin-norepinephrine reuptake inhibitors (SNRIs) and SSRIs, including sertraline HCl , can precipitate serotonin syndrome, a potentially life-threatening condition .

      Warning 2

      Drugs that interfere with serotonin reuptake inhibition, including sertraline HCl, increase the risk of bleeding events. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk.

      Warning 3

      Hyponatremia may occur as a result of treatment with SNRIs and SSRIs, including sertraline HCl. Cases with serum sodium lower than 110 mmol/L have been reported .

      Seroft Tablets Additional Information

      Pregnancy category

      Always consult your physician before using any medicine.

      Storage (YES/NO)

      Store this medicine at room temperature, away from direct light and heat.

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