BONE HEALTH: Vitamin D plays an essential role in maintaining a strong mineralized skeleton for humans. BODYACHES & PAINS: Vitamin D exerts anatomic, hormonal, neurological, and immunological influences on pain manifestation, thereby playing a role in the etiology and maintenance of chronic pain states and associated comorbidity. HEART HEALTH: Multiple studies have linked Vitamin D3 deficiency with higher risk of high blood pressure and cardiomyopathy. IMMUNE HEALTH: Vitamin D3 has been defined as natural immune modulator, and upon activation of Vitamin D3 receptors (VDRs), it regulates Calcium metabolism, cellular growth, proliferation and apoptosis, and other immunological functions. DIABETES MELLITUS: Vitamin D3 supplementation helps increase the body's sensitivity to the blood sugar-regulating hormone, insulin, thus reducing the risk of diabetes, researchers have found. Vitamin D3 stimulates insulin secretion. This is via direct action on pancreatic beta cells and indirectly by normalizing calcium levels extracellularly. The evidence of the aforementioned has been confirmed by finding Vitamin D3 receptors (VDRs) on the insulin promoter gene, the presence of Vitamin D3 receptors (VDRs) on the pancreatic beta cells.

Like all medicines, this medicine can cause side effects, although not everybody gets them. Side effects with Vitamin D3 may include:
Uncommon side effects (affecting less than 1 in 100 people) : Too much calcium in your blood (hypercalcemia). You may feel or be sick, lose your appetite, have constipation, stomach ache, feel very thirsty, have muscle weakness, drowsiness or confusion - too much calcium in your urine (hypercalciuria).
Rare side effects (affecting less than 1 in 1000 people) : - skin rash - itching - hives

If you are allergic (hypersensitive) to vitamin D or any of the other ingredients in the capsules.
- Have high levels of vitamin D in your blood (hypervitaminosis D)
- Have high blood levels of calcium (hypercalcemia) or high urine levels of calcium (hypercalciuria)
- Have kidney stones or serious kidney problems

Talk to your doctor before taking Vitamin D3 if: - You have kidney damage or disease. Your doctor will need to measure the levels of calcium in your blood or urine.
- You are already taking additional doses of calcium or vitamin D. Whilst you are taking cholecalciferol your doctor will monitor your blood levels of calcium to make sure they are not too high.

Talk to your doctor before taking Vitamin D3 if you are being treated for heart disease.

Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time each day.

This Medicine should not be use in Pregnancy.

In particular the following medicines may interact with Vitamin D3: Heart medicines (cardiac glycosides such as digoxin) , Medicines to treat epilepsy (such as phenytoin) or medicines to make you sleep (barbiturates such as phenobarbitone) as these medicines can decrease the effect of vitamin D , Glucocorticoids (steroid hormones such as hydrocortisone or prednisolone). These can decrease the effect of vitamin D. Thiazide diuretics (Water tablets) can increase the concentration of calcium in the blood , Laxatives (such as para n oil) or a cholesterol lowering drug called cholestyramine may reduce the absorption of vitamin D , Actinomycin (a medicine used to treat some forms of cancer) and imidazole antifungals (medicines such as clotrimazole and ketoconazole used to treat fungal diseases) as they may interfere with the metabolism of vitamin D.